VITAMIN D DEFICIENCY IN CRITICALLY ILL CHILDREN

In critical illness, there also is evidence of rapid falls in circulating 25(OH) D concentrations. So, we aim to assess the prevalence of VDD in pediatric ICU (PICU) patients and to determine whether there is any relationship between VDD and illness severity and mortality. This is a case control study that included 40 children: 20 patient admitted to pediatric intensive care unit in Qena university at time of the study (from January 2018 till December 2018) compared to 20 apparently healthy well-matched children regarding age and sex to be compared as controls. All patients subjected to: Full history, detailed physical examination, diagnostic modalities as: laboratory investigation and severity of illness was assessed with the pediatric risk of mortality III. Our study included 40 children with the age of patients ranged from 5 months to 12years with mean +/- SD 3.7 ±3 year. Male patient’s represented 70%.In our study, the prevalence of vitamin D deficiency among critically ill children was 70 %we did not find significant correlation between 25(OH) vitamin D and pediatric risk of mortality III (PRISM III). Vitamin D Deficiency (VDD) prevalence was reported in 70% of the critically ill patients, and it was observed to be related to multiple organ dysfunctions and rapid clinic alt deterioration.